Xylocaine W/ Adrenaline

Xylocaine W/ Adrenaline

lidocaine + epinephrine

Manufacturer:

Aspen Pharmacare Asia

Distributor:

Cordial Trading
/
Primal
Concise Prescribing Info
Contents
Lidocaine HCl w/ adrenaline
Indications/Uses
Production of local or regional anaesth by following techniques: Infiltration, IV regional anaesth, peripheral nerve block eg, intercostal block; major plexus block eg, brachial plexus block; epidural block & subarachnoid block.
Dosage/Direction for Use
The lowest dosage that results in effective anaesth should be used. Infiltration 100 mL of 0.5% inj; 50 mL of 1% inj or 25 mL of 2% inj. Brachial plexus block 20-40 mL of 1% inj; 15-30 mL of 1.5% inj. Nerve block Intercostal & paravertebral: 3-5 mL/segment of 1% inj. Pudendal: 10-20 mL of 1% inj. Stellate ganglion block Cervical: 5-10 mL of 1% inj. Lumbar: 5-20 mL of 1% inj. Epidural anaesth Thoracic: 15-30 mL of 1% inj. Lumbar: 15-30 mL of 1.5% inj; 10-25 mL of 2% inj. Caudal: 15-30 mL of 1.5% inj. Lumbar & caudal epidural analgesia 15-30 mL of 1% inj.
Contraindications
Known hypersensitivity to local anaesth of the amide-type or Na metabisulfite; sympathomimetic amines. Not to be used for epidural & spinal anaesth in patients w/ uncorrected hypotension or coagulation disorders or receiving anticoagulation treatment; inflammation &/or sepsis in the region of the proposed inj &/or in the presence of septicaemia. Conditions where the production or exacerbation of tachycardia may prove fatal eg, thyrotoxicosis or severe heart disease or when maternal BP exceeds 130/80 mmHg in obstet. In areas of the body w/ compromised blood supply or supplied by end arteries eg, fingers, toes, nose, ears or penis. IV regional techniques. Patients w/ cerebral arteriosclerosis.
Special Precautions
Post-op IA continuous infusion. Monitor CV & resp vital signs, patient's state of consciousness, neurologic impairment. Patient w/ epilepsy, impaired cardiac conduction, bradycardia, severe shock or digitalis intoxication, Stokes-Adam syndrome or Wolff-Parkinson-White syndrome. Central nerve blocks. Preexisting abnormal neurological pathology. Hepatic & renal impairment. Foetal bradycardia/tachycardia. Monitor ECG for patient under antiarrythmic drugs class III. Severe & untreated HTN, arteriosclerotic heart disease, cerebral vascular insufficiency, heart block, advanced diabetes, poorly controlled thyrotoxicosis, ventricular fibrillation, prefibrillatory rhythm, tachycardia, MI, phenothiazine-induced circulatory collapse & prostatic hypertrophy. Porphyric patients. May impair ability to drive or operate machinery.
Adverse Reactions
CNS manifestations either excitatory &/or depressant. CV manifestations, mainly depressant. Maternal hypotension. Allergic reaction. Neurologic manifestations.
Drug Interactions
Antiarrhythmic drugs eg, disopyramide, procainamide, mexiletine; amiodarone; β-adrenoreceptor antagonists eg, propranolol & metoprolol; cimetidine; anticonvulsive agents, phenytoin, phenobarb, primidone, carbamazepine; inhalational anaesth; skeletal muscle relaxant; CNS-acting drugs, phenothiazine, butyrophenone; oxytocic drug of the ergot-type; adrenergic neuron blocker; cardiac glycosides; β-blockers; quinidine; hypoglycaemics; alkaline soln.
MIMS Class
Anaesthetics - Local & General
ATC Classification
N01BB52 - lidocaine, combinations ; Belongs to the class of amides. Used as local anesthetics.
Presentation/Packing
Form
Xylocaine W/ Adrenaline inj
Packing/Price
(single-dose) 20 mL x 5 × 1's
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